Seeking Health

Optimal Liposomal Glutathione Plus 150 ml

• Highly bioavailable reduced form of glutathione
• Innovative formula with incredible assimilability
• Powerful antioxidant system of the organism
• Detoxification of the organism from xenobiotics
• Optimization of energy processes
• Strengthening of the immune system
• Elimination of heavy metals from the organism
• Protection and support of liver work
• Decrease of homocysteine level
• Slows down aging processes
• Support of the work of mitochondria
• Ideal for sportsmen

Seeking Health Optimal Liposomal Glutathione is a dietary supplement containing reduced glutathione in the highly assimilable liposomal form, at the dose of 250 mg and also vitamin B2, selenium, molybdenum and pyrroloquinoline quinone (PQQ), demonstrating synergistic effect. Optimal level of glutathione in the organism is essential to maintain oxidation-reduction potential in cells and for proper processes of detoxification.

Glutathione (GSH) is a tripeptide made of cysteine, glycine and glutamic acid. It is present in all tissues and organs of the human being. The majority is located in the liver, where it is coupled with xenobiotics (the unfamiliar substances for the organism), i.a. with free radicals, unsaturated aliphatic hydrocarbons, halogen aliphatic and aromatic hydrocarbons or epoxides. Xenobiotics coupled with glutathione are excreted with urine (after being transformed to mercapturic acids) or bile. These processes take place in the II phase of xenobiotic biotransformation. An incredibly important role in this processes is played by the group of enzymes, glutathione S-transferase (GST). These enzymes are found i.a. in the liver, kidneys, intestines and lungs. They catalyze reactions of coupling of nucleophilic glutathione with electrophilic molecules of xenobiotics, created in the I phase of biotransformation. The coupling of xenobiotics with glutathione has mainly detoxicating character. By means of this process, glutathione protects cells from the harmful effect of free radicals and other reactive molecules.

The amount of glutathione in the liver is correlated with the antioxidant capacity of this organ. Its deficiency results in non-complete metabolism of xenobiotics. A classic example is the reaction of glutathione with an active metabolite of paracetamol – N-acetyl-p-benzoquinone imine (NAPQI), which is hepatotoxic. In case of excessively low amount of NAPQI, it is not totally bound and inactivated, which results in liver necrosis.

Riboflavin (vitamin B2) is the most important B-group vitamin. The main function of riboflavin is its participation in the processes of oxidation and reduction. It constitutes a prosthetic group (non-protein enzyme part) of flavoproteins, to which there belong, i.a. NADH reductase of cytochrome C, amino acid oxidase, acetyl-CoA dehydrogenase. Acetyl-CoA dehydrogenase takes part in fatty acid metabolism. Riboflavin, by the influence on the availability of NADPH, indirectly influences the concentration of glutathione. Moreover, it is essential for biochemical changes of vitamin B6 and folic acid, for the synthesis of niacin from tryptophan and also for the proper functioning of the eyesight.

Along with vitamin B6, B12 and folic acid, riboflavin takes part in homocysteine metabolism, lowering its level. Homocysteine constitutes a marker for many diseases. Increased concentration of homocysteine may contribute to the development of many diseases, i.a. cardiovascular diseases, neurodegenerative diseases, depression and cancers. Excessively high level of homocysteine, causing oxidative stress, leads to depleting the supplies of glutathione.

Selenium is a microelement, which is essential for the proper functioning of the organism. Its proper biological role is its participation in antioxidant systems of cells and transformations of thyroid and steroid hormones. It is the component of four glutathione peroxidase isoenzymes. Appropriate concentration of selenium in blood serum conditions optimal pace of glutathione peroxidase reaction.

Selenium, as an element of the antioxidant system of the organism, takes part in metabolic transformations of each cells and decreases toxic influence of xenobiotics, especially heavy metals. Moreover, by being the component of proteins dependent on selenium, it positively influences the immune system. Deficiency of this element in the organism may lead to storing excessive amount of free radicals, which entails negative consequences for the organism.

Molybdenum is an element, appearing in the organism in trace amounts. It constitutes a cofactor for many enzymes of the organism. It is engaged in the metabolism of sulfuric compounds, the level of which has influence on the concentration of glutathione, the most abundantly appearing intracellular thiol in mammals (the substance containing sulfur).

PQQ (pyrroloquinoline quinone) is a recently discovered substance. In structure, it is close to coenzyme Q10 and vitamin K. In the era of mitochondrial medicine development, the role of PQQ is increased. This compound may have positive influence on energy processes taking place in mitochondria. It stimulates biogenesis of mitochondria in aging cells. It fights free radicals and is a strong antioxidant.

In the studies on rats, PQQ caused considerable improvement of memory. PQQ also influences the decrease of CRP level (C-reactive protein), appearing in blood under the influence of inflammation, produced in the liver, adipose cells and arterial vessels. Marking CRP level is an element of diagnostics of circulatory system diseases. Moreover, CRP is conducive to storing fatty tissue and inhibits the development of muscle tissue. Human organism cannot synthesize PQQ, therefore more and more often it is classified to the group of vitamins.

Liposomes are vesicles spontaneously appearing from phospholipids (lipids creating cell membranes). In pharmaceutics, they found application as innovative drug carriers. A substance “closed” in a liposome freely permeates biological membranes of cells, due to the similarity in structure. It is very beneficial from the point of view of bioavailability. A substance closed in a liposome is protected by this structure from oxidative degradation and demonstrates longer effect.

To sum up, Seeking Health Optimal Liposomal Glutathione is a dietary supplement containing effective ingredients supporting one of the strongest antioxidant systems of the organism – glutathione. It is especially recommended to sportsmen, people taking medicines, with lowered immunity, prone to the harmful environmental factors and toxins, i.e. heavy metals, in order to support the work of the liver and optimization of metabolic processes.