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Isobutyryl Thiamine Disulfide even though it is a water-soluble derivative of vitamin B1 (thiamine) it is an oil soluble, what is making it easier to cross the blood-brain barrier and increase the level of thiamine and thiamine phosphate esters and neurotransmitter activity. The use of the preparation allows for effective treatment of chronic fatigue effects (including male sexual dysfunction), slowing down in the initial stages of neurological disorders. In the sports supplementation it is used to improve exercise capacity, as an ingredient of stimulating supplements (such as fat burners, creatine stacks and nitrogen boosters).